Russian Journal of Biological Physics and Chemisrty Russian Journal of Biological Physics and Chemisrty АКТУАЛЬНЫЕ ВОПРОСЫ БИОЛОГИЧЕСКОЙ ФИЗИКИ И ХИМИИ 2499-9962 54064 БИООРГАНИЧЕСКАЯ, БИОФИЗИЧЕСКАЯ И МЕДИЦИНСКАЯ ХИМИЯ BIOORGANIC, BIOPHYSICAL AND MEDICINAL CHEMISTRY БИООРГАНИЧЕСКАЯ, БИОФИЗИЧЕСКАЯ И МЕДИЦИНСКАЯ ХИМИЯ INVESTIGATION OF ANTIRADICAL AND ANTIBACTERIAL ACTIVITY OF HONEY FROM DIFFERENT REGIONS OF AZERBAIJAN ИССЛЕДОВАНИЕ АНТИРАДИКАЛЬНОЙ АКТИВНОСТИ (АР) И АНТИМИКРОБНЫХ (АМ) СВОЙСТВ МЕДА РАЗЛИЧНЫХ РЕГИОНОВ АЗЕРБАЙДЖАНА Чырагова С Р Chyragova S R chyragova71@mail.ru Абдуллаева Ф Г Abdullayeva F G Ганбаров Х Г Ganbarov Kh G Абдуллаев Х Д Abdullayev Kh D Бакинский государственный университет ru Baku State University ru Бакинский государственный университет ru Baku State University ru Бакинский государственный университет ru Baku State University ru Бакинский государственный университет ru Baku State University ru 25 12 2016 25 12 2016 1 2 57 60 20 12 2016 20 12 2016 https://rusjbpc.ru/en/nauka/article/54064/view

В представленной работе впервые дан анализ антирадикальной (АР) и антимикробной (АМ) активности меда, собранного из различных районов Азербайджана. Исследования проводили с использованием метода, основанного на тушении стабильного свободного радикала DРРН (2/2 дифенил-1-пикрилгидрозил, C18H12N5O6). Анализ IC50 для образца меда по отношению IC50 стандартного тушителя тролокса (аналого витамина Е) показал, что обрацы меда по эффективности АР, располагаются в следующей последовательности: Закатала (горный) > Белокан (лесной) > Исмаиллы > Белокан (горный) > Закатала (низменный) > Гедабек > Самух > Ленкорань. Наибольшей АМ активностью против Escherichia coli и Staphylococcus aureus обладает мёд, производимый в горных районах. Предполагается, что наблюдаемая высокая АР и АМ активнсти высокогорных образцов меда, связаны с растительностью, способствующей накоплению в продуктах меда - бактерицидных, а также фенольных соединений и флавоноидов.

In the present study for the first time we showed antiradical activity (AR) and antibacterial (AB) activity analyses of the honey from different regions of the Azerbaijan Republic. Research was carried out by usage stable free radical DPPH (2/2 diphenil-1-picrilhydrosyl, C18H12N5O6) assay. The comparative analyses of honey samples and standard TROLOX (analogue of E vitamin) showed that honey samples demonstrate their AR activity in the following order: Zagatala (mountain) > Balakan (forest) > Ismailli > Balakan (mountain) > Zagatala (plain) > Gadabey > Samukh > Lankaran. The highest AM activity against Escherichia coli and Staphylococcus aureus were detected for honey from mountain regions. The close correlation of the specifics of the region vegetation with AR and AB activities were found out. It’s believed that vegetation of the high mountain area caused the accumulation of flavonoids, bactericidal and phenolic compounds in the honey.

 мед метод DPPH антирадикальная активность (AP) антимикробная активность (АМ) патогенные бактерии honey DPPH assay antiradical (AR) antibacterial activity (AB) pathogenic bacteria

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