<!DOCTYPE article
PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20190208//EN"
       "JATS-journalpublishing1.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.4" xml:lang="en">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Russian Journal of Biological Physics and Chemisrty</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Russian Journal of Biological Physics and Chemisrty</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>АКТУАЛЬНЫЕ ВОПРОСЫ БИОЛОГИЧЕСКОЙ ФИЗИКИ И ХИМИИ</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2499-9962</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">54532</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>МЕДИЦИНСКАЯ БИОФИЗИКА И БИОФИЗИЧЕСКАЯ ХИМИЯ</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>MEDICAL BIOPHYSICS AND BIOPHYSICAL CHEMISTRY</subject>
    </subj-group>
    <subj-group>
     <subject>МЕДИЦИНСКАЯ БИОФИЗИКА И БИОФИЗИЧЕСКАЯ ХИМИЯ</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">The influence of illumination spectra on sclera physico-mechanical properies on japanese quail chick model</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Влияние разных типов освещения на механические свойства склеры на примере японского перепела Coturnix japonica</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Храмцова</surname>
       <given-names>Е А</given-names>
      </name>
      <name xml:lang="en">
       <surname>Khramtsova</surname>
       <given-names>E A</given-names>
      </name>
     </name-alternatives>
     <email>alyonushk@gmail.com</email>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Крашенинников</surname>
       <given-names>С В</given-names>
      </name>
      <name xml:lang="en">
       <surname>Krasheninnikov</surname>
       <given-names>S V</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Петронюк</surname>
       <given-names>Ю С</given-names>
      </name>
      <name xml:lang="en">
       <surname>Petronyuk</surname>
       <given-names>Y S</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Трофимова</surname>
       <given-names>Н Н</given-names>
      </name>
      <name xml:lang="en">
       <surname>Trofimova</surname>
       <given-names>N N</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-4"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Гурьева</surname>
       <given-names>Т С</given-names>
      </name>
      <name xml:lang="en">
       <surname>Gurieva</surname>
       <given-names>T S</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-5"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Дадашева</surname>
       <given-names>О А</given-names>
      </name>
      <name xml:lang="en">
       <surname>Dadasheva</surname>
       <given-names>O A</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-6"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Левин</surname>
       <given-names>В М</given-names>
      </name>
      <name xml:lang="en">
       <surname>Levin</surname>
       <given-names>V M</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-7"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Григорьев</surname>
       <given-names>Т Е</given-names>
      </name>
      <name xml:lang="en">
       <surname>Grigoriev</surname>
       <given-names>T E</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-8"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Зак</surname>
       <given-names>П П</given-names>
      </name>
      <name xml:lang="en">
       <surname>Zak</surname>
       <given-names>P P</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-9"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Институт биохимической физики им. Н.М. Эмануэля РАН</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">N.M. Emanuel Institute of Biochemical Physics Russian Academy of Sciences</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Национальный исследовательский центр «Курчатовский институт»</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">National Research Centre &quot;Kurchatov Institute&quot;</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">Институт биохимической физики им. Н.М. Эмануэля РАН</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">N.M. Emanuel Institute of Biochemical Physics Russian Academy of Sciences</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-4">
    <aff>
     <institution xml:lang="ru">Институт биохимической физики им. Н.М. Эмануэля РАН</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">N.M. Emanuel Institute of Biochemical Physics Russian Academy of Sciences</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-5">
    <aff>
     <institution xml:lang="ru">Институт медико-биологических проблем РАН</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">Research Center Institute of Biomedical Problems, Russian Academy of Sciences</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-6">
    <aff>
     <institution xml:lang="ru">Институт медико-биологических проблем РАН</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">Research Center Institute of Biomedical Problems, Russian Academy of Sciences</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-7">
    <aff>
     <institution xml:lang="ru">Институт биохимической физики им. Н.М. Эмануэля РАН</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">N.M. Emanuel Institute of Biochemical Physics Russian Academy of Sciences</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-8">
    <aff>
     <institution xml:lang="ru">Национальный исследовательский центр «Курчатовский институт»</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">National Research Centre &quot;Kurchatov Institute&quot;</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-9">
    <aff>
     <institution xml:lang="ru">Институт биохимической физики им. Н.М. Эмануэля РАН</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">N.M. Emanuel Institute of Biochemical Physics Russian Academy of Sciences</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2020-06-25T20:22:29+03:00">
    <day>25</day>
    <month>06</month>
    <year>2020</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2020-06-25T20:22:29+03:00">
    <day>25</day>
    <month>06</month>
    <year>2020</year>
   </pub-date>
   <volume>5</volume>
   <issue>2</issue>
   <fpage>331</fpage>
   <lpage>334</lpage>
   <history>
    <date date-type="received" iso-8601-date="2020-06-20T20:22:29+03:00">
     <day>20</day>
     <month>06</month>
     <year>2020</year>
    </date>
    <date date-type="accepted" iso-8601-date="2020-06-20T20:22:29+03:00">
     <day>20</day>
     <month>06</month>
     <year>2020</year>
    </date>
   </history>
   <self-uri xlink:href="https://rusjbpc.ru/en/nauka/article/54532/view">https://rusjbpc.ru/en/nauka/article/54532/view</self-uri>
   <abstract xml:lang="ru">
    <p>В работе представлены предварительные данные о влиянии спектрального состава повседневного освещения (синее освещение - 450 нм; красное освещение - 630 нм, дневной свет лампы накаливания для контрольной группы) на постнатальное развитие склеры глаза японского перепела Coturnix coturnix japonica dom. , как широко используемой модели для исследования развития структур глаза и модели заболеваний зрительного аппарата. В условиях in situ исследованы толщины склер неинвазивными методами с использованием импульсной акустической микроскопии, что позволяет провести измерения с минимальными искажениями. После выделения склер были проведены механические испытания и определены основные физико-механические характеристики. Показано, что на 23 сутки постнатального развития при синем освещении при сравнении с красным наблюдается уменьшение толщины склеры (∆14%) в сочетании с понижением ее эластичности (∆7%). Результаты механических испытаний были проинтерпретированы в рамках модели высокоэластичности, основанной на не-Гауссовой статистике, оценивающей расположение основных структурных элементов склеры (внеклеточного матрикса) и выдвинуты предположения об особенностях развития склер при разном спектральном освещении. Работа выполнена в рамках задач по моделированию детской миопии.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>The research presents preliminary data about influence of everyday illumination spectra on the postnatal development of the sclera (blue light - 450 nm; long-wave red light - 630 nm and daylight for the control group). Japanese quail ( Coturnix coturnix japonica dom. ) are widely used animal model for studying of eye development structures and various eye disorders. The thickness of sclera was studied by non-invasive methods using scanning impulse acoustic microscopy, which allows to take measurements with minimal distortion in situ . After the sclera was isolated, mechanical tests were carried out and the main physico-mechanical characteristics were determined. It was shown that on the 23rd day of postnatal development in blue light conditions the decrease in the thickness of the sclera (∆14%) is observed in combination with a decrease in its elasticity (∆7%). Interpretation of mechanical test results was made via a model of high elasticity based on non-Gaussian statistics that estimates the locations of the main structural elements of the sclera (extracellular matrix). The model revealed some features of the sclera development under different spectral illumination. The work was performed as part of the tasks of kid's myopia modeling.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>склера</kwd>
    <kwd>японский перепел</kwd>
    <kwd>внеклеточный матрикс</kwd>
    <kwd>акустическая микроскопия</kwd>
    <kwd>физико-механические свойства</kwd>
    <kwd>нативная ткань</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>sclera</kwd>
    <kwd>quail</kwd>
    <kwd>extracellular matrix</kwd>
    <kwd>ultrasound microscopy</kwd>
    <kwd>physico-mechanical characteristics</kwd>
    <kwd>native tissue</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
  <ref-list>
   <ref id="B1">
    <label>1.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">
            
              Summers Rada J., Shelton S., Norton T. The sclera and myopia. Experimental Eye Research, 2006, vol. 82, pp. 185-200.
            
          </mixed-citation>
     <mixed-citation xml:lang="en">
            
              Summers Rada J., Shelton S., Norton T. The sclera and myopia. Experimental Eye Research, 2006, vol. 82, pp. 185-200.
            
          </mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B2">
    <label>2.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">
            
              Wisely C., Sayed J., Tamez H., Zelinka C., Abdel-Rahman M., Fischer A., Cebulla C. The chick eye in vision research: An excellent model for the study of ocular disease. J. Prog Retin Eye Res, 2017, vol. 61, pp. 72-97.
            
          </mixed-citation>
     <mixed-citation xml:lang="en">
            
              Wisely C., Sayed J., Tamez H., Zelinka C., Abdel-Rahman M., Fischer A., Cebulla C. The chick eye in vision research: An excellent model for the study of ocular disease. J. Prog Retin Eye Res, 2017, vol. 61, pp. 72-97.
            
          </mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B3">
    <label>3.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">
            
              Ostrin L. Ocular and systemic melatonin and the influence of light еxposure. Clin. Exp. Opt., 2019, vol. 102, pp. 99-108.
            
          </mixed-citation>
     <mixed-citation xml:lang="en">
            
              Ostrin L. Ocular and systemic melatonin and the influence of light exposure. Clin. Exp. Opt., 2019, vol. 102, pp. 99-108.
            
          </mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B4">
    <label>4.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">
            
              Sereznikova N., Pogodina L., Lipina T., Trofimova N., Gurieva T., Zak P. Age-related adaptive responses of mitochondria of the retinal pigment epithelium to the everyday blue LED lighting. Doklady Biological Sciences, 2017, vol. 475, no. 1, pp. 141-143.
            
          </mixed-citation>
     <mixed-citation xml:lang="en">
            
              Sereznikova N., Pogodina L., Lipina T., Trofimova N., Gurieva T., Zak P. Age-related adaptive responses of mitochondria of the retinal pigment epithelium to the everyday blue LED lighting. Doklady Biological Sciences, 2017, vol. 475, no. 1, pp. 141-143.
            
          </mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B5">
    <label>5.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">
            
              Rucker F. Monochromatic and white light and the regulation of eye growth, Exp.Eye Res., 2019, vol. 184, pp. 172-182.
            
          </mixed-citation>
     <mixed-citation xml:lang="en">
            
              Rucker F. Monochromatic and white light and the regulation of eye growth, Exp.Eye Res., 2019, vol. 184, pp. 172-182.
            
          </mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B6">
    <label>6.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">
            
              Khramtsova E.A., Zak P.P., Petronyuk J.S., Trofimova N.N., Krasheninnikov S.V., Titiov S.A., Gurieva T.S., Dadasheva O.A., Grigoriev T.E., Levin V.M. Light induced myopia in Japanese quail chicks by acoustic microscopy. Proceedings of VII International Conference AIS-2020, in press.
            
          </mixed-citation>
     <mixed-citation xml:lang="en">
            
              Khramtsova E.A., Zak P.P., Petronyuk J.S., Trofimova N.N., Krasheninnikov S.V., Titiov S.A., Gurieva T.S., Dadasheva O.A., Grigoriev T.E., Levin V.M. Light induced myopia in Japanese quail chicks by acoustic microscopy. Proceedings of VII International Conference AIS-2020, in press.
            
          </mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B7">
    <label>7.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">
            
              Elias-Zuniga A. A non-Gaussian network model for rubber elasticity. Polymer, 2006, vol. 47, pp. 907-914.
            
          </mixed-citation>
     <mixed-citation xml:lang="en">
            
              Elias-Zuniga A. A non-Gaussian network model for rubber elasticity. Polymer, 2006, vol. 47, pp. 907-914.
            
          </mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B8">
    <label>8.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">
            
              Fratzl P. (eds), Collagen: Structure and Mechanics. Springer, Boston, 2008, pp. 359-397.
            
          </mixed-citation>
     <mixed-citation xml:lang="en">
            
              Fratzl P. (eds), Collagen: Structure and Mechanics. Springer, Boston, 2008, pp. 359-397.
            
          </mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B9">
    <label>9.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">
            
              Khramtsova E., Morokov E., Lukanina K., Grigoriev T., Petronyuk Y., Shepelev A., Gubareva E., Kuevda E., Levin V., Chvalun S. Impulse acoustic microscopy: A new approach for investigation of polymer and natural scaffolds. Polymer Engineering and Science, 2017, vol. 57, no. 7, pp. 709-715.
            
          </mixed-citation>
     <mixed-citation xml:lang="en">
            
              Khramtsova E., Morokov E., Lukanina K., Grigoriev T., Petronyuk Y., Shepelev A., Gubareva E., Kuevda E., Levin V., Chvalun S. Impulse acoustic microscopy: A new approach for investigation of polymer and natural scaffolds. Polymer Engineering and Science, 2017, vol. 57, no. 7, pp. 709-715.
            
          </mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B10">
    <label>10.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">
            
              Morokov E., Khramtsova E., E. Kuevda, Gubareva E., Grigoriev T., Lukanina K., Levin V. Noninvasive ultrasound imaging for assessment of intact microstructure of extracellular matrix in tissue engineering. Artif Organs, 2019, vol. 43, no. 11, pp. 1104-1110.
            
          </mixed-citation>
     <mixed-citation xml:lang="en">
            
              Morokov E., Khramtsova E., E. Kuevda, Gubareva E., Grigoriev T., Lukanina K., Levin V. Noninvasive ultrasound imaging for assessment of intact microstructure of extracellular matrix in tissue engineering. Artif Organs, 2019, vol. 43, no. 11, pp. 1104-1110.
            
          </mixed-citation>
    </citation-alternatives>
   </ref>
  </ref-list>
 </back>
</article>
