Russian Journal of Biological Physics and Chemisrty Russian Journal of Biological Physics and Chemisrty АКТУАЛЬНЫЕ ВОПРОСЫ БИОЛОГИЧЕСКОЙ ФИЗИКИ И ХИМИИ 2499-9962 54145 МОЛЕКУЛЯРНАЯ БИОФИЗИКА И ФИЗИКА БИОМОЛЕКУЛ MOLECULAR BIOPHYSICS AND PHYSICS OF BIOMOLECULES МОЛЕКУЛЯРНАЯ БИОФИЗИКА И ФИЗИКА БИОМОЛЕКУЛ Application of transfer matrix formalism for analysis of multicomponent binding of biologically active molecules to DNA Применение формализма трансфер-матриц к анализу многокомпонентного связывания биологически активных молекул с ДНК Бучельников А С Buchelnikov A S buchelnikov@bsu.edu.ru Белгородский государственный национальный исследовательский университет ru Belgorod State National Research University ru 25 06 2017 25 06 2017 2 1 178 181 20 06 2017 20 06 2017 https://rusjbpc.ru/en/nauka/article/54145/view

Статистико-механический формализм трансфер-матриц впервые использован для получения обобщенного выражения классической модели МакГи - фон Хиппеля для случая некооперативного и неспецифического связывания лигандов различных типов с решеточным биополимером.

The generalized derivation of classical McGhee - von Hippel equation for the first time was performed by means of statistical-mechanical transfer matrix formalism. The equation is applicable for study of non-cooperative and non-specific binding of ligands of various types to a lattice biopolymer.

 биополимер лиганд константа ассоциации статистическая сумма трансфер-матрица biopolymer ligand association constant partition function transfer matrix

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