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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Russian Journal of Biological Physics and Chemisrty</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Russian Journal of Biological Physics and Chemisrty</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>АКТУАЛЬНЫЕ ВОПРОСЫ БИОЛОГИЧЕСКОЙ ФИЗИКИ И ХИМИИ</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2499-9962</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">83373</article-id>
   <article-id pub-id-type="doi">10.29039/rusjbpc.2023.0630</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>МЕДИЦИНСКАЯ БИОФИЗИКА И БИОФИЗИЧЕСКАЯ ХИМИЯ</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>MEDICAL BIOPHYSICS AND BIOPHYSICAL CHEMISTRY</subject>
    </subj-group>
    <subj-group>
     <subject>МЕДИЦИНСКАЯ БИОФИЗИКА И БИОФИЗИЧЕСКАЯ ХИМИЯ</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">COMPARISON OF MELATONIN PHOTODEGRADATION BETWEEN SUNLIGHT  AND UV IRRADIATION</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>СРАВНЕНИЕ ФОТОДЕГРАДАЦИИ МЕЛАТОНИНА ПОД ВОЗДЕЙСТВИЕМ СОЛНЕЧНОГО СВЕТА И УЛЬТРАФИОЛЕТОВОГО ИЗЛУЧЕНИЯ</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Баррера Кирос</surname>
       <given-names>Р. А.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Barrera Quiroz</surname>
       <given-names>R. A.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Эрнандес Сантьяго</surname>
       <given-names>Адриан Аполинар</given-names>
      </name>
      <name xml:lang="en">
       <surname>Ernandes Sant'yago</surname>
       <given-names>Adrian Apolinar</given-names>
      </name>
     </name-alternatives>
     <bio xml:lang="ru">
      <p>доктор философских наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>doctor of philosophical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Зентено Матео</surname>
       <given-names>Б. </given-names>
      </name>
      <name xml:lang="en">
       <surname>Zenteno Mateo</surname>
       <given-names>B. </given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Гонсалес Фуэнтес</surname>
       <given-names>М. А.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Gonzalez Fuentes</surname>
       <given-names>M. A.</given-names>
      </name>
     </name-alternatives>
     <email>marcos.gonzalez@correo.buap.mx</email>
     <xref ref-type="aff" rid="aff-4"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Мендес Альборес</surname>
       <given-names>А. </given-names>
      </name>
      <name xml:lang="en">
       <surname>Mendez Albores</surname>
       <given-names>A. </given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-5"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Мендес Альборес</surname>
       <given-names>Э. </given-names>
      </name>
      <name xml:lang="en">
       <surname>Mendez Albores</surname>
       <given-names>E. </given-names>
      </name>
     </name-alternatives>
     <email>erika.mendez@correo.buap.mx</email>
     <xref ref-type="aff" rid="aff-6"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Автономный университет Пуэбла</institution>
     <city>Пуэбла</city>
     <country>Мексика</country>
    </aff>
    <aff>
     <institution xml:lang="en">Meritorious Autonomous University of Puebla</institution>
     <city>Puebla</city>
     <country>Mexico</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Автономный университет Пуэбла</institution>
     <city>Пуэбла</city>
     <country>Мексика</country>
    </aff>
    <aff>
     <institution xml:lang="en">Meritorious Autonomous University of Puebla</institution>
     <city>Puebla</city>
     <country>Mexico</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">Автономный университет Пуэбла</institution>
     <city>Пуэбла</city>
     <country>Мексика</country>
    </aff>
    <aff>
     <institution xml:lang="en">Meritorious Autonomous University of Puebla</institution>
     <city>Puebla</city>
     <country>Mexico</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-4">
    <aff>
     <institution xml:lang="ru">Автономный университет Пуэбла</institution>
     <city>Пуэбла</city>
     <country>Мексика</country>
    </aff>
    <aff>
     <institution xml:lang="en">Meritorious Autonomous University of Puebla</institution>
     <city>Puebla</city>
     <country>Mexico</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-5">
    <aff>
     <institution xml:lang="ru">Автономный университет Пуэбла</institution>
     <city>Пуэбла</city>
     <country>Мексика</country>
    </aff>
    <aff>
     <institution xml:lang="en">Meritorious Autonomous University of Puebla</institution>
     <city>Puebla</city>
     <country>Mexico</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-6">
    <aff>
     <institution xml:lang="ru">Автономный университет Пуэбла</institution>
     <city>Пуэбла</city>
     <country>Мексика</country>
    </aff>
    <aff>
     <institution xml:lang="en">Meritorious Autonomous University of Puebla</institution>
     <city>Puebla</city>
     <country>Mexico</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2024-05-27T09:21:53+03:00">
    <day>27</day>
    <month>05</month>
    <year>2024</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2024-05-27T09:21:53+03:00">
    <day>27</day>
    <month>05</month>
    <year>2024</year>
   </pub-date>
   <volume>8</volume>
   <issue>3</issue>
   <fpage>337</fpage>
   <lpage>341</lpage>
   <history>
    <date date-type="received" iso-8601-date="2023-07-28T00:00:00+03:00">
     <day>28</day>
     <month>07</month>
     <year>2023</year>
    </date>
   </history>
   <self-uri xlink:href="https://rusjbpc.ru/en/nauka/article/83373/view">https://rusjbpc.ru/en/nauka/article/83373/view</self-uri>
   <abstract xml:lang="ru">
    <p>Мелатонин синтезируется главным образом в шишковидной железе, сетчатке, пищеварительном тракте и коже. Этот гормон широко назначают в терапевтических целях, таких как лечение циркадных ритмов, аритмии при межконтинентальных перелетах (синдром смены часовых поясов) и нарушений сна. В результате пандемии COVID-19 потребление этого гормона было увеличено до 300% в дозах выше 5 мг в день, поскольку его использовали для лечения бессонницы и в качестве вспомогательного средства при лечении SARS-CoV-2. Таким образом, ожидается, что этот гормон будет присутствовать в поверхностных водоемах в качестве загрязнителя. Хотя сообщается, что мелатонин может быть фотолабилен, его фотохимия до конца не изучена. По этой причине в данной работе оценивалась фотодеградация мелатонина в растворе. Растворы мелатонина с концентрацией 20 и 500 мкМ, растворенные в воде, подвергали воздействию солнечного света и ультрафиолетового излучения, а деградацию контролировали с помощью спектрофотометрии и общего органического углерода.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Melatonin is synthesized mainly in the pineal gland, retina, digestive tract, and skin. This hormone is widely prescribed for therapeutic applications such as treating circadian rhythm, intercontinental flight dysrhythmia (jet lag syndrome), and sleep disorders. As a result of the COVID-19 pandemic, the consumption of this hormone was increased up to 300% in doses higher than 5 mg day because it was used to treat insomnia and as an adjunct to treat SARS-CoV-2. Therefore, this hormone is expected to be present in surface water bodies as a pollutant. Although it is reported that melatonin can be photolabile, its photochemistry has not been exhaustively studied. For this reason, the photodegradation of melatonin in solution was evaluated in this work.  Solutions of 20 and 500 μM of melatonin dissolved in water were exposed to sunlight and UVA irradiation, and the degradation was monitored by spectrophotometry and total organic carbon.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>мелатонин</kwd>
    <kwd>фотодеградация</kwd>
    <kwd>спектрофотометрия</kwd>
    <kwd>средство лечения SARS-CoV-2</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>melatonin</kwd>
    <kwd>photodegradation</kwd>
    <kwd>spectrophotometry</kwd>
    <kwd>adjunct to treat SARS-CoV-2</kwd>
   </kwd-group>
  </article-meta>
 </front>
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