BIOFUNCTIONAL ALIPHATIC POLYESTER-BASED PARTICLES - PERSPECTIVE DRUG DELIVERY SYSTEMS
Abstract and keywords
Abstract (English):
The paper describes the basic principles as applied to create polymeric micro- and nanoparticles to deliver both low molecular weight and high molecular weight drugs into the body. For micro- and nanoparticles obtaining the methods of single emulsion and nanoprecipitation were used, respectively. We used single emulsion method to encapsulate hydrophobic drugs the, and double emulsion method to include hydrophilic molecules and proteins. Furthermore, results of biological tests of the obtained polymer particles for therapy of tuberculosis are presented.

Keywords:
biodegradable particles, drug delivery systems
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References

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