Spatial structure of N-terminal domains of CTCF insulator proteins from higher metazoans was studied using small-angle X-ray scattering (SAXS). In contrast to N-terminal domains of Drosophila CTCF protein, similar domains from other animals were unable to form oligomers and mainly are unfolded. Multimerization ability probably is unique for insects.
multimerization, small-angle X-ray scattering, chromatin
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