In the present study we investigated the effect of the spatial-hindered phenol - sodium anphen (1- carboxy-1- (N-methylamide) -2- (3’,5’-di-tert-butyl-4-hydroxy-phenyl sodium propanat) on the functional state of rat liver mitochondria. Stress actions caused 3-4 fold increase in fluorescence intensity of lipid peroxidation products in the membranes of these organelles. The preparation decreased the LPO intensity to control values, which contributed to maintaining high functional activity of mitochondria. The prevention of mitochondrial dysfunction, probable, was associated with an increased resistance of animals to stress factors. It is assumed that the protective activity of sodium anphen is due to its antioxidant properties.
anphen, adaptogen
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