With the use of atomic-emission spectrometry, the blood plasma samples from the patients with brain aneurysms have been analyzed. The integrated estimate for metabolism of the essential elements has been given. The enhanced content of aluminum, iron, calcium, zinc and the lowered content of magnesium has been revealed for all the patients both before and after the operation. The revealed microelementoses can affect particular features of the clinical disease course, pointing to the advisability of using complexes for correction of the mineral metabolism in addition to the adopted therapy. The morphology of the dried blood plasma drops has been studied and the structural peculiarities of the drops have been exhibited. For the spatial calcium distribution over the surface and within the layers of the dried blood plasma drops the quantitative results have been obtained. Besides, it has been demonstrated that the use of laser atomic-emission spectrometry enables one to have quantitative estimates of variations in protein centers. This method has shown itself as an effective highly sensitive diagnostic instrument. The obtained experimental data may form the basis for further development of the methods for early detection of disturbances in the functional resources of a human organism enabling selection of timely and adequate rehabilitation measures.
atomic-emission spectral analysis, blood plasma, biological fluids, drop morphology, laser atomic-emission spectrometry, spatial distribution of calcium, layer-by-layer analysis
1. Rumyanceva S.A., Afanas'ev V.V., Silina E.V., Eliseev E.V. Metody racional'noy farmakokorrekcii i profilaktiki vtorichnoy ishemii i vazospazma u bol'nyh s narusheniyami mozgovogo krovoobrascheniya razlichnogo haraktera. Trudnyy pacient, 2010, № 6, s. 19-25. [Rumyantseva S.A., Afanasiev V.V., Silina E.V., Eliseev E.V. The methods of rational pharmacocorrection and prophylaxis of the secondary ischemia and vasospasm of the patients suffering from disturbances in cerebral circulation of different character. Difficult patients, 2010, no. 6, pp. 19-25. (In Russ.)]
2. Ugol'nik T.S., Chubukova T.N. Mehanizmy apoptoza pri ishemii golovnogo mozga. Problemy zdorov'ya i ekologii, 2009, № 3(21), s. 94-99. [Ugolnik T.S., Chubukova T.N. The apoptosis mechanisms on cerebral ischemia. Problems of health and ecology, 2009, no. 3(21), pp. 94-99. (In Russ.)]
3. Novikova L.B., Gromova O.A., Kuramshina D.B. Rol' mikroelementov pri ishemicheskom insul'te. Medicinskiy Vestnik Bashkortostana, 2010, t. 5, № 4, s. 156-160. [Novikova L.B., Gromova O.A., Kuramshina D.B. The role of microelements in ischemic stroke. Bashkortostan medical journal, 2010, vol. 5, no. 4, pp. 156-160. (In Russ.)]
4. Kudrin A.V., Gromova O.A. Mikroelementy v nevrologii, M.: GEOTAR-Media, 2006, 304 s. [Kudrin A.V., Gromova O.A. Microelements in neurology, M.: GEOTAR-media, 2006, 304 p. (In Russ.)]
5. Suter P.M. The effects of potassium, magnesium, calcium and fiber on risk of stroke. Nutr. Rev., 1999, vol. 57, no. 3, pp. 84-88.
6. Gelmers H. J. Effect of calcium antagonists on cerebral circulation. Amer. J. Cardiol, 1987, vol. 59, pp. 173-176.
7. Maksimov S.A. Morfologiya tverdoy fazy biologicheskih zhidkostey kak metod diagnostiki v medicine. Byulleten' sibirskoy mediciny, 2007, № 4, s. 80-85. [Maksimov S.A. Morphology of the solid phase of biological fluids as a diagnostic method in medicine. Siberian Medical Bulletin, 2004, no. 4, pp. 80-85. (In Russ.)]
8. Kraevoy S.A., Koltovoy N.A. Diagnostika po kaple krovi. Kristallizaciya biozhidkostey. V 4 kn. M., 2013. Kniga 1. Otkrytaya kaplya, s. 67-71. [Kraevoy S.A., Koltovoy N.A. Diagnosis on the basis of one blood drop. Crystallization of biological fluids. In 4 books. M., 2013. Book 1. Open drop. pp. 67-71. (In Russ.)]
9. Sidorenko Yu.S., Shihlyarova A.I., Sergost'yanc G.Z. Regional'nye osobennosti morfologii krovi bol'nyh rakom legkogo: processy samoorganizacii v dinamike hirurgicheskogo lecheniya i autogemotransfuzii. Vestnik yuzhnogo nauchnogo centra RAN, 2005, t. 1, № 4, s. 64-71. [Sidorenko Yu.S., Shikhlyarova A.I., Segostjantz G.Z. J. of the SRC of RAS, vol. 1, no. 4, 2005, pp. 64-71. (In Russ.)]
10. Buloychik Zh.I., Veremchuk A.N., Russko T.A., Maslova G.T., Mavrichev A.S. Morfologicheskoe i spektrometricheskoe izuchenie obrazcov vysohshih kapel' krovi onkologicheskih bol'nyh. Vestnik BGU. Seriya 1, 2015, № 2, s. 24-30. [Buloichik J.I., Veremchuk A.N., Russko T.A., Maslova G.T., Mavrichev A.S. Morfological and spectrometric studies of the dried blood-drop samples of oncological patients. J. of BSU. Ser. 1, 2015, no. 2, pp. 24-30. (In Russ.)]
11. Savkov A.V., Sergey M.A., Buloychik Zh.I., Maslova G.T., Mavrichev A.S., Derzhavec L.A. Ispol'zovanie morfostrukturnogo analiza i lazernoy atomno-emissionnoy spektrometrii vysohshih kapel' plazmy krovi dlya diagnostiki raka prostaty. Vestnik BGU. Ser. 1, 2016, № 3, s. 51-62. [Savkov A.V., Sergei M.A., Buloichik J.I., Maslova G.T., Mavrichev A.S. Vestnik BGU. Ser. 1, 2016, no. 3, pp. 51-62. (In Russ.)]
12. Buloychik Zh.I., Maslova G.T., Korzyuk V.V., Sergey M.A., Mavrichev A.S., Derzhavec L.A. Primenenie atomno-emissionnoy spektrometrii vysohshih kapel' plazmy krovi v diagnostike i lechenii opuholey mozga. Zh. BGU, Fizika, 2017, № 2, s. 17-26. [Buloichik J.I., Maslova G.T., Sergey M.A., Korzuk V.V., Mavrichev A.S., Derzhavets L.A. Using of atomic-emission spectrometry of the dried blood plasma drops in diagnosis and treatment of brain tumors. J. of BSU. Physics, 2017, no. 2, pp. 17-26. (In Russ.)]
