CHANGES OF INDICES OF FERROKINETICS, TOTAL ANTIOXIDANT ACTIVITY AND LACTOFERRIN CONCENTRATION IN THE PLASMA OF CHILDREN WITH IRON DEFICIENCY IN PROGRESS OF TREATMENT
Abstract and keywords
Abstract (English):
The investigation of ferrokinetics, total antioxidant activity, and plasma lactoferrin concentration in the plasma of children 0-17 years old with iron deficiency (iron-deficiency anemia and latent iron deficiency) before and after treatment was made. It was shown that after treatment with ferro drug group of adolescent patients, ferritin (from 5.9 to 10.3 ng/ml) and iron (from 11.5 to 23.5 mmol/l) concentration in blood serum increased, but total plasma antioxidant activity decreased in contrast with data before treatment (~20%, Р < 0.05). While iron deficiency lactoferrin concentration in plasma raised with a maximum in a group of children 0-3-month-old. During ferrotherapy lactoferrin concentration also increased in comparison with the results before treatment. Obtained results showed the necessity of considering the level total antioxidant activity of plasma children with iron deficiency during treatment with fero drugs.

Keywords:
iron deficiency, ferrokinetics, total antioxidant activity, lactoferrin, children
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