In this work it was found that patients at the time of admission to the hospital have changes in the local spatial distribution of calcium and the morphological structure of dehydrating drops of biofluids, which are characterized by the appearance of wide, three-beam and tourniquet cracks in whole blood and a loss of plasma symmetry. An initially low superoxide dismutase activity was detected in the blood of patients, which normalized after a course of treatment with the inclusion of intravenous or supravenous laser irradiation of blood in addition to standard therapy.
laser atomic emission spectroscopy, dehydration of biofluid drops, morphological structure, chronic cerebral ischemia, oxidative stress, laser hemotherapy
1. Voskresenskaya O.N., Zaharova N.B., Ivanov M.V. Mehanizmy formirovaniya hronicheskoy ishemii golovnogo mozga pri arterial'noy gipertenzii. Zhurn. nevrologii i psihiatrii im. Korsakova, 2017, № 2, s. 68-71.
2. Levin O.S., Shtul'man D.R. Nevrologiya. Spravochnik prakticheskogo vracha, 10 izdanie. M.: «MEDpress-inform», 2016, s. 406-416.
3. Nechipurenko N.I. Rol' kislorodzavisimyh processov v patogeneze hronicheskoy ishemii golovnogo mozga. Nevrologiya i neyrohirurgiya. Vostochnaya Evropa, 2012, № 3, s. 150-159.
4. Chen S.D., Yang D. I., Lin T.K., Shaw F.Z., Liou C.W., Chuang Y.C. Roles of oxidative stress, apoptosis, PCG-1α and mitochondrial biogenesis in cerebral ischemia. Int. J.Mol. Sci., 2011, vol. 12 (10), p. 7199.
5. Nikitin A.V., El'zhurkaev A.A. Nadvennoe nizkointensivnoe lazernoe izluchenie v kompleksnom lechenii ishemicheskoy bolezni serdca. Vestnik novyh medicinskih tehnologiy, 2013, № 1.
6. Nechipurenko N.I., Stepanova Yu.I., Vasilevskaya L.A., Pashkovskaya I.D. Lazernaya gemoterapiya pri ishemicheskih cerebrovaskulyarnyh zabolevaniyah (ekperimental'nye i klinicheskie aspekty). Minsk: Biznesofset, 2010, 192 s.
7. Pashkovskaya I.D., Nechipurenko N.I., Vasilevskaya L.A. Effekty infrakrasnogo lazernogo izlucheniya pri eksperimental'noy cerebral'noy ishemii. Zdravoohranenie, 2010, № 2., s. 74-78.
8. Shabalin V.N., Shatohina S.N. Morfologiya biologicheskih zhidkostey cheloveka. M.: Hrizostom, 2001, 302 s.
9. Buloychik Zh.I., Zazhogin A.P., Nechipurenko N.I., Patapovich M.P., Pashkovskaya I.D. Morfologicheskoe i spektrofotometricheskoe issledovanie plazmy krovi pacientov s anevrizmoy sosudov golovnogo mozga. Zhurnal BGU. Fizika, 2018, № 1, s. 9-17.
10. Kostyuk V.A., Potapovich A.I., Kovaleva Zh.V. Prostoy i chuvstvitel'nyy metod opredeleniya aktivnosti superoksiddismutazy, osnovannyy na reakcii okisleniya kvercetina. Vopr. med. himii, 1990, t. 36, № 2, s. 88-91.
11. Korolyuk M.A., Ivanova L.I., Mayrova I.G. Metod opredeleniya aktivnosti katalazy. Laboratornoe delo, 1988, № 1, s. 16-19. [Korolyuk M.A., Ivanova L.I., Mayrova I.G. Method for determination of catalase activity. Laboratory science, 1988, no. 1, pp. 16-19. (In Russ.)]
12. Kostyuk V.A., Potapovich A.I. Opredelenie produktov perekisnogo okisleniya lipidov s pomosch'yu tiobarbiturovoy kisloty v anaerobnyh usloviyah. Vopr. med. himii, 1987, № 3, s. 115-118.
13. Maksimov S.A. Morfologiya tverdoy fazy biologicheskih zhidkostey kak metod diagnostiki v medicine. Byulleten' sibirskoy mediciny, 2007, № 4, s. 80-85. [Maksimov S.A. Morphology of the solid phase of biological fluids as a diagnostic method in medicine. Bulletin of Siberian Medicine, 2007, no. 4, pp. 80-85. (In Russ.)]
14. Kamyshnikov V.S., Kiselev P.A., Kohnovich N.N., Oreshko N.A., Yuraga T.M. Metabolicheskie faktory formirovaniya patologicheskih sostoyaniy, svyazannyh s narusheniem antioksidantnogo statusa organizma: metody ocenki. Laboratornaya diagnostika. Vostochnaya Evropa, 2014, № 3, s. 116-133.
