Polychlorinated biphenyls (PCBs) are amongst the most dangerous toxic substances of anthropogenic origin incoming into coastal marine waters from various polluting sources. Even extremely small doses of PCBs induce changes in the physiological and biochemical processes in hydrobionts tissues, exert toxic, mutagenic and carcinogenic influences. Investigations of the biochemical response in tissues of the bivalve mollusks, living in a high concentration conditions of PCBs created in the conducted experiment, are of importance to understand the reorganization metabolism mechanisms and adaptive reactions, occurring in the body of hydrobionts being exposed to toxicants. This article is aimed at studying the impact of PCBs on the prooxidant-antioxidant system parameters (activity of superoxide dimutase, catalase, the level of lipid peroxidation and oxidized proteins) in hepatopancreas of the Black Sea mussel Mytilus galloprovincialis in the acute toxicological experiment. It has been established that M. galloprovincialis has high toxicoresistance to PCBs. At the same time observations from our studies showed that, upon exposure to different concentrations of PCBs there was a development of oxidative stress carried out by shifting the prooxidant- antioxidant balance towards the intensification of lipid peroxidation and oxidative modification of proteins also an increase in the SOD activity existing as the adaptive compensatory reaction of the organism to the toxic substances in the hepatopancreas of mollusks.
polychlorinated biphenyls, mussel Mytilus galloprovincialis, prooxidant-antioxidant system
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