UDC 577

FUNCTIONAL ACTIVITY OF RECOMBINANT CHEMERIC OMPF PORIN FROM YERSINIA PSEUDOTUBERCULOSIS Functional activity of recombinant chemeric OmpF porin from Yersinia Pseudotuberculosis

Published in Russian Journal of Biological Physics and Chemisrty · Volume 2, Issue 1 · Pages 251–255 · Rubric: MOLECULAR BIOPHYSICS AND PHYSICS OF BIOMOLECULES
Received: 20.06.2017 Accepted: 20.06.2017 Published: 25.06.2017 Language of publication: RUS
He interaction of recombinant (R-OmpF) and chimeric OmpF porin from outer membrane of Yersinia pseudotuberculosis (Ch-OmpF) with negatively charged liposomes was studied. It was shown that the porin spatial structure in Ch-OmpF supported by DsbC protein-chaperone in the presence of lipid bilayer can take a functional activity conformation. The effectiveness of pore formation depended on the composition of the liposomal membrane and the presence of lipopolysaccharide.
porin, pore-forming activity, liposomes, lipopolysaccharide
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