STUDY ACTIVITY OF INFLUENZA NEURAMINIDASE IN AQUEOUS SOLUTION AND AGGREGATES SURFACTANTS
Abstract and keywords
Abstract (English):
It is known that the functioning of many proteins and enzymes depends on the degree of hydration of their surfaces. So, Jurginis Y.I. with colleagues was shown the dependence of the activity of alpha-chymotrypsin on the magnitude of elasticity of water vapor. The influence of hydration on the functional activity of the viral antigenic proteins is currently unknown. In this case, the hydration can influence the binding of particular antigenic protein to a receptor "target cells" and affect the interpretation of data to determine the activity of the antigenic protein.

Keywords:
), degree of hydration, neuraminidase (NA), the model of the adsorption of the Brunauer-Emmett-Teller (BET), surfactants
Text
Publication text (PDF): Read Download
References

1. Ostarman L.A. Metody issledovaniya belkov i nukleinovyh kislot: Elektroforez i ul'tracentrifugirovanie (prakticheskoe posobie). M.: Nauka, 1981, c. 288. [Ostarman L.A. Methods of study of proteins and nucleic acids: Electrophoresis and Ultracentrifugation (practical guide). Moscow: Nauka, 1981, p. 288. (In Russ.)]

2. Hurgin Yu.I., Roslyakov V.Ya., Klyachko-Gurvich A.L., Brueva T.R. Adsorbciya parov vody α-himotripsinom i lizocimom. Biohimiya, 1972, t. 37, c. 485-492. [Hurgin Yu.I., Roslyakov V.Ya., Klyachko-Gurvich A.L., Brueva T.R. The adsorption of water vapor by α-chymotrypsin and lysozyme. Biohimiy, 1972, vol. 37, pp. 485-492. (In Russ.)]

3. Meyhi B.V.Dzh. Virusologiya: Metody. M.: Mir, 1988, 192 s. [Meyhi B.V.Dzh. Virusologiya: Metodyi. Moscow: Mir, 1988, 192 r. (in Russ.)]

4. Tompa K., Bokor M., Verebélyi T., Tompa P. Water rotation barriers on protein molecular surfaces. Chemical Physics, 2015, vol. 448, pp. 15-25.

5. Walde P., Peng Q., Fadnavis N.W., Battistel E., Luisi P.L. Structure and activity of trypsin in reverse micelles. Eur. J. Biochem, 1988, vol. 173, pp. 401-409.

6. Mao Q., Walde P., Luisi P.L. Kinetic behaviour of a-chymotrypsin in reverse micelles. Eur. J. Biochem, 1992, vol. 208, pp. 165-170.

7. Bru R., Walde P. Product inhibition of a-chymotrypsin in reverse micelles. Eur. J. Biochem, 1991, vol. 199, pp. 95-103.


Login or Create
* Forgot password?