Moscow, Moscow, Russian Federation
Moscow, Moscow, Russian Federation
The method of preparation of highly diluted solutions, by iterative dilution accompanied by intense mechanical action is described. The results of high-frequency electrical conductivity and dielectric permittivity of L and D isomers of alanine and valine are presented. The absence of dielectric increment in all samples indicates the absence of mesoparticles with high dielectric permittivity in solutions. A non-monotonic, complex dependence of electrical conductivity on the number of N dilution iterations is recorded. This type of dependence persists at large N, when the concept of the solute concentration loses its meaning, which indicates changes in the composition of aqueous solutions under mechanical impact. Repeated measurements of samples stored in closed vials in closed cardboard boxes at room conditions revealed long-term evolutionary processes in aqueous solutions. The peculiarity of the evolution of the electrical conductivity of alanine and valine solutions, in comparison with the previously studied potentiated diclofenac solutions, consists in a decrease in electrical conductivity over time, which contradicts the additional dissolution of carbon dioxide from the atmosphere when opening vials and dissolving glass. There were no differences in the properties of L and D isomers of alanine and valine solutions.
dilute aqueous solutions, intensive mechanical impact, amino acids, diclofenac, electrical conductivity, reactive oxygen species
1. Lobyshev V.I. On the problem of low concentrations on biological activity. Russian Journal of Biological Physics And Chemistry, 2020, vol. 5, no. 3, pp. 390-398. (In Russ.)
2. Xibo Yan, Delgado M., Aubry J., Gribelin O., Stocco A., Da Cruz F.B., Bernard J., Ganachaud F. Central Role of Bicarbonate Anions in Charging Water/Hydrophobic Interfaces. J. Phys. Chem. Lett., 2018, vol. 9, pp. 96-103, doi:https://doi.org/10.1021/acs.jpclett.7b02993.
3. Khare P., Kumar N., Kumari K.M., Srivastava S.S. Atmospheric formic and acetic acid: on overview. Reviews of Geophysics, 1999, vol. 37, no. 2, pp. 227-248.
4. Rajendran E.S. Nanodynamics. Mohna Publ., Kerala, India, 2015.
5. Bruskov V.I., Chernikov A.V., Ivanov V.E., Karmanova E.E., Gudkov S.V. Formation of the reactive species of oxygen, nitrogen, and carbon dioxide in aqueous solutions under physical impacts. Phys. Wave Phenom., 2020, vol. 28, no. 2, pp. 103-106, doi:https://doi.org/10.3103/s1541308x2002003x.
6. Gudkov S.V., Nikita V. Penkov N.V., Baimler I.V., Lyakhov G.A., Pustovoy V.I., Simakin A.V., Sarimov R.M., Scherbakov I.A. Effect of Mechanical Shaking on the Physicochemical Properties of Aqueous Solutions. Int. J. Mol. Sci., 2020, vol. 21, p. 8033, doi:https://doi.org/10.3390/ijms21218033.
7. Lobyshev V.I. Dielectric Characteristics of Highly Diluted Aqueous Diclofenac Solutions in the Frequency Range of 20 Hz to 10 MHz. Physics of Wave Phenomena, 2019, vol. 27, no. 2, pp. 119-127. doi:https://doi.org/10.3103/S1541308X19020067.
8. Lobyshev V.I. Non-monotonous impedance patterns of diclofenac centesimal potentiated solutions and their evolution. Water. Special edition, 2022, doi:https://doi.org/10.14294/WATER.2022.S4.
9. Lobyshev V.I. Evolution of High-Frequency Conductivity of Pure Water Samples Subjected to Mechanical Action: Effect of a Hypomagnetic Filed. Physics of Wave Phenomena, 2021, vol. 29, no. 2, pp. 98-101, doi:https://doi.org/10.3103/S1541308X21020084.
10. Lobyshev V.I. Electrical Properties of Heavy Water Samples Subjected to Vigorous Shaking during Successive Dilutions. Physics of Wave Phenomena, 2022, vol. 30, no. 3, pp. 141-144.
