Electron probe microanalysis was applied to study the kinetics of changes in potassium and sodium concentration in muscle cells of isolated heart from Wistar rat during experimental ischemia. Hypoxic perfusion without glucose was shown to evoke the potassium deficiency and sodium accumulation in cardiac myocells. Short_term action (10 min) of strophanthin (0.1 mM/l) recovered Na/K balance in ischemic myocells.
Electron Probe Microanalysis (EPMA), cardiac ischemia, myocell, cytoplasmic K/Na balance, Na+/K+- ATPase, strophanthin
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